Publications 

Baethge C, Baldessarini RJ, Mathiske-Schmidt K, Hennen J, Berghofer A, Muller-Oerlinghausen B, Bschor T, Adli M, Bauer M. Long-term combination therapy versus monotherapy with lithium and carbamazepine in 46 bipolar I patients. J Clin Psychiatry 2005;66:174-182

Baethge C, Gruschka P, Berghoefer A, Bauer M, Mueller-Oerlinghausen B, Bschor T, Smolka MN. Prophylaxis of schizoaffective disorder with lithium or carbamazepine: outcome after long-term follow-up. J Affect Disord 2004;79:43-50

Baethge C, Gruschka P, Smolka MN, Berghöfer A, Bschor T, Müller-Oerlinghausen B, Bauer M. Effectiveness and outcome predictors of long-term lithium prophylaxis in unipolar major depressive disorder. J Psychiatry Neurosci 2003;28:355-361

Baethge C, Smolka MN, Gruschka P, Berghöfer A, Schlattmann P, Bauer M, Altshuler L, Grof P, Müller-Oerlinghausen B. Does prophylaxis delay in bipolar disorders influence outcome? Results from a long-term study of 147 patients. Acta Psychiatr Scand 2003:107:260-267

Baethge C, Tondo L, Bratti IM, Bschor T, Bauer M, Viguera MC, Baldessarini RJ. Prophylaxis-latency and outcome in bipolar disorders. Can J Psychiatry 2003;48:449-457

Bauer M, Glenn T, Grof P, Pfennig A, Rasgon NL, Marsh W, Munoz RA, Sagduyu K, Alda M, Quiroz D, Sasse J, Whybrow PC. Self-reported data from patients with bipolar disorder: Frequency of brief depression. J Affect Disord. 2007;101:227-233

Bauer M, Rasgon N, Grof P, Glenn T, Lapp M, Marsh W, Munoz R, Suwalska A, Baethge C, Bschor T, Alda M, Whybrow PC. Do antidepressants influence mood patterns? A naturalistic study in bipolar disorder. Eur Psychiatry 2006;21:262-269

Bauer M, Grof P, Rasgon NL, Marsh W, Munoz RA, Sagduyu K, Alda M, Quiroz D, Glenn T, Baethge C, Whybrow PC. Self-reported data from patients with bipolar disorder: impact on minimum episode length for hypomania. J Affect Disord. 2006;96:101-105

Bauer M, Grof P, Gyulai L, Rasgon N, Glenn T, Whybrow PC. Using technology to improve longitudinal studies: self-reporting with ChronoRecord in bipolar disorder. Bipolar Disord 2004;6:67-74

Bauer M, Alda M, Priller J, Young LT; International Group For The Study Of Lithium Treated Patients (IGSLI) Implications of the neuroprotective effects of lithium for the treatment of bipolar and neurodegenerative disorders. Pharmacopsychiatry 2003;36 Suppl 3:S250-S254

Berghöfer A, Alda M, Adli M, Baethge C, Bauer M, Bschor T, Grof P, Müller-Oerlinghausen B, Rybakowski JK, Suwalska A, Pfennig A: Stability of lithium treatment in bipolar disorder – long-term follow-up of 346 patients. Int J Bip Disord 2013, 1:11, doi:10.1186/2194-7511-1-11

Berghöfer A, Müller-Oerlinghausen B. Is there a loss of efficacy of lithium in patients treated for over 20 years? Neuropsychobiology 2000;42(suppl.1):46-49

Berghöfer A, Müller-Oerlinghausen B. No loss of efficacy after discontinuation and reinstitution of long-term lithium treatment? In: Gallicchio VS, Birch NJ (eds.) Lithium. Biochemical and Clinical Advances. Weidner Publishing Group, Cheshire, Conn 1996,pp.39-46

Berghöfer A, Kossmann B, Müller-Oerlinghausen B. Course of illness and pattern of recurrences in patients with affective disorders during long-term lithium prophylaxis: A retrospective analysis over 15 years. Acta Psychiatr Scand 1996, 93, 349-354

Bernhard B, Schaub A, Kummler P, Dittmann S, Severus E, Seemuller F, Born C, Forsthoff A, Licht RW, Grunze H. Impact of cognitive-psychoeducational interventions in bipolar patients and their relatives. Eur Psychiatry 2006;21:81-86

Bieling PJ, MacQueen GM, Marriot MJ, Robb JC, Begin H, Joffe RT, Young LT. Longitudinal outcome in patients with bipolar disorder assessed by life-charting is influenced by DSM-IV personality disorder symptoms. Bipolar Disord 2003;5:14-21

Bratti IM, Baldessarini RJ, Baethge C, Tondo L: Pretreatment episode count and response to lithium treatment in manic-depressive illness. Harv. Rev. Psychiatry 2003; 11:245–56

Bschor T: Lithium in the Treatment of Major Depressive Disorder. Drugs 2014;74:855-862

Bschor T, Uhr M, Baethge C, Lewitzka U, Ising M, Erbe S, Winkelmann P, Ritter D: Acute antidepressive efficacy of lithium monotherapy, not citalopram, depends on recurrent course of depression. J Clin Psychopharmacol 2013;33:38-44

Deshauer D, Duffy A, Alda M, Grof E, Albuquerque J, Grof P. The cortisol awakening response in bipolar illness: a pilot study. Can J Psychiatry 2003;48:462-466

Deshauer D, Grof E, Alda M, Grof P: Patterns of DST positivity in remitted affective disorders. Biol Psychiatry 1999;45:1023-1029

Garnham J, Munro A, Slaney C, Macdougall M, Passmore M, Duffy A, O’Donovan C, Teehan A, Alda M. Prophylactic treatment response in bipolar disorder: Results of a naturalistic observation study. J Affect Disord 2007 Apr 16;

Glenn T, Whybrow PC, Rasgon N, Grof P, Alda M, Baethge C, Bauer M. Approximate entropy of self-reported mood prior to episodes in bipolar disorder. Bipolar Disord 2006;8(5 Pt 1):424-429

Grof P. Selecting effective long-term treatment for bipolar patients: monotherapy and combinations. J Clin Psychiatry 2003;64 (Suppl 5):53-61

Grof P, Robbins W, Alda M, Berghöfer A, Vojtechovsky M, Nilsson A, Robertson C. Protective effect of pregnancy in women with lithium-responsive bipolar disorder. J Affect Disord 2000;61:31-39

Grof P, Alda M. Discrepancies in the efficacy of lithium (letter to the editor). Arch Gen Psychiatry 2000;57:191

Grof P. Excellent lithium responders: People whose lives have been changed by lithium prophylaxis. In: Birch NJ, Gallicchio VS, Becker RW (eds.) Lithium: 50 years of psychopharmacology. New perspectives in biomedical and clinical research. Weidner, Cheshire 1999, pp.36-51

Grof P, Alda M, Ahrens B. Clinical course of affective disorders: were Emil Kraepelin and Jules Angst wrong? Psychopathology 1995;28 (Suppl 1):73-80

Grof P, Alda M, Grof E, Fox D, Cameron P. The challenge of predicting response to stabilising lithium treatment. The importance of patient selection. Br J Psychiatry 1993;21:16-19

Hartong EG, Moleman P, Hoogduin CA, Broekman TG, Nolen WA; LitCar Group. Prophylactic efficacy of lithium versus carbamazepine in treatment-naive bipolar patients. J Clin Psychiatry. 2003 Feb;64(2):144-51.

Kleindienst N, Severus WE, Greil W. Are serum levels related to the polarity of recurrence in bipolar disorders? Evidence form a multicenter trial. Int Clin Psychopharmacol 2007;22:125-131

Kleindienst N, Severus WE, Möller HJ, Greil W. Is polarity of recurrence related to serum lithium level in patients with bipolar disorder? Eur Arch Psychiaty Clin Neurosci 2005;255:72-74

Lewitzka U, Scheffczyk R, Ritter D, Doucette S, Bauer M, Bschor T: No correlation between lithium serum levels and psychopathological features during the euthymic interval of patients with recurrent affective disorder. Pharmacopsychiatry 2012;45:1-6

Licht RW, Vestergaard P, Rasmussen NA, Jepsen K, Brodersen A, Hansen PE. A lithium clinic for bipolar patients: 2-year outcome of the first 148 patients. Acta Psychiatr Scand 2001;104:387-390.

MacQueen GM, Marriott M, Begin H, Robb J, Joffe RT, Young LT. Subsyndromal symptoms assessed in longitudinal, prospective follow-up of a cohort of patients with bipolar disorder. Bipolar Disord 2003;5:349-355

Nolen WA. More robust evidence for the efficacy of lithium in the long-term treatment of bipolar disorder: should lithium (again) be recommended as the single preferred first-line treatment? Int J Bipolar Disord. 2015 Jan 31;3:1.

Nolen WA, Weisler RH. The association of the effect of lithium in the maintenance treatment of bipolar disorder with lithium plasma levels: a post hoc analysis of a double-blind study comparing switching to lithium or placebo in patients who responded to quetiapine (Trial 144). Bipolar Disord. 2013 Feb;15(1):100-9.

Passmore MJ, Garnham J, Duffy A, MacDougall M, Munro A, Slaney C, Teehan A, Alda M. Phenotypic spectra of bipolar disorder in responders to lithium versus lamotrigine. Bipolar Disord 2003;5:110-114

Pfennig A, Schlattmann P, Alda M, Grof P, Glenn T, Müller-Oerlinghausen B, Suwalska A, Rybakowski J, Willich S N, Bauer M, Berghöfer A. Influence of atypical features on the quality of prophylactic effectiveness of long-term lithium treatment in bipolar disorders. Bipolar Disord 2010;12(4): 390-396

Rasgon N, Bauer M, Glenn T, Elman S, Whybrow PC. Menstrual cycle related mood changes in women with bipolar disorder. Bipolar Disord 2003;5:48-52

Ruzickova M, Slaney C, Garnham J, Alda M. Clinical features of bipolar disorder with and without comorbid diabetes mellitus. Can J Psychiatry 2003;48:458-461

Rybakowski JK, Chlopocka-Wozniak M, Suwalska A. The prophylactic effect of long-term lithium administration in bipolar patients entering treatment in the 1970s and 1980s. Bipolar Disord 2001;3:63-67

Rybakowski JK, Dyson WL, Amsterdam JD. Alexithymia and somatic conditions in patients with affective illnesses during lithium prophylaxis. Psychother Psychosom 1988;49:1-5

Rybakowski JK, Chlopocka-Wozniak M, Kapelski Z, Strzyzewski W. The relative prophylactic efficacy of lithium against manic and depressive recurrences in bipolar patients. Int Pharmacopsychiatry 1980;15:86-90

Schaub, R, Berghöfer A, Müller-Oerlinghausen B. What do patients in a lithium outpatient clinic know about lithium? J Psychiatry Neurosci 2001;26:319-324

Schumann C, Lenz G, Berghöfer A, Müller-Oerlinghausen B. Non-adherence with long-term prophylaxis: a 6-year naturalistic follow-up study of affectively ill patients. Psychiatr Research 1999;89:247-257

Severus WE, Lipkovich IA, Licht RW, Young AH, Greil W, Ketter T, Deberdt W, Tohen M. In search of optimal lithium levels and olanzapine doses in the long-term treatment of bipolar I disorder. A post-hoc analysis of the maintenance study by Tohen et al. 2005. Eur Psychiatry 2010;25:443-449

Severus WE, Kleindienst N, Seemüller F, Frangou S, Möller HJ, Greil W. What ist he optimal serum lithium level in the long-term treatment of bipolar disorder- a review? Bipolar Disord 2008;10:231-237

Severus WE, Kleindienst N, Greil W. Re-evalutation of randomized controlled trials of lithium monotherapy. Bipolar Disord 2006;8:519-520

Severus WE, Grunze H, Kleindienst N, Frangou S, Moeller HJ. Ist he prophylactic antidepressant efficacy of lithium in bipolar I disorder dependent on study design and lithium level? J Clin Psychopharmacol 2005;25:457-462

Tohen M, Greil W, Calabrese JR, Sachs GS, Yatham LN, Oerlinghausen BM, Koukopoulos A, Cassano GB, Grunze H, Licht RW, Dell’Osso L, Evans AR, Risser R, Baker RW, Crane H, Dossenbach MR, Bowden CL. Olanzapine versus lithium in the maintenance treatment of bipolar disorder: a 12-month, randomized, double-blind, controlled clinical trial. Am J Psychiatry 2005;162:1281-1290

Van der Loos ML, Mulder P, Hartong EG, Blom MB, Vergouwen AC, van Noorden MS, Timmermans MA, Vieta E, Nolen WA; LamLit Study Group.. Efficacy and safety of two treatment algorithms in bipolar depression consisting of a combination of lithium, lamotrigine or placebo and paroxetine. Acta Psychiatr Scand. 2010 Sep;122(3):246-54.

Van der Loos ML, Mulder PG, Hartong EG, Blom MB, Vergouwen AC, de Keyzer HJ, Notten PJ, Luteijn ML, Timmermans MA, Vieta E, Nolen WA; LamLit Study Group. Efficacy and safety of lamotrigine as add-on treatment to lithium in bipolar depression: a multicenter, double-blind, placebo-controlled trial. J Clin Psychiatry. 2009 Feb;70(2):223-31.

Vestergaard P, Licht RW, Brodersen A, Rasmussen NA, Christensen H, Arngrim T, Gronvall B, Kristensen E, Poulstrup I, Wentzer Licht R. Outcome of lithium prophylaxis: a prospective follow-up of affective disorder patients assigned to high and low serum lithium levels. Acta Psychiatr Scand 1998;98:310-315

Weisler RH, Nolen WA, Neijber A, Hellqvist A, Paulsson B; Trial 144 Study Investigators.. Continuation of quetiapine versus switching to placebo or lithium for maintenance treatment of bipolar I disorder (Trial 144: a randomized controlled study). J Clin Psychiatry. 2011 Nov;72(11):1452-64.

Whybrow PC, Grof P, Gyulai L, Rasgon N, Glenn T, Bauer M. The electronic assessment of the longitudinal course of bipolar disorder: the ChronoRecord software. Pharmacopsychiatry 2003;36 Suppl 3:S244-S249

Wilting I, Heerdink ER, Mersch PP, den Boer JA, Egberts AC, Nolen WA. Association between lithium serum level, mood state, and patient-reported adverse drug reactions during long-term lithium treatment: a naturalistic follow-up study. Bipolar Disord. 2009 Jun;11(4):434-40.

Zakowska-Dabrowska T, Rybakowski J. Lithium-induced EEG changes: relation to lithium levels in serum and red blood cells. Acta Psychiatr Scand 1973;49:457-465

Ahrens B, Müller-Oerlinghausen B. Does lithium exert an independent antisuicidal effect? Pharmacopsychiatry 2001;34:132-136

Ahrens B, Grof P, Möller HJ, Müller-Oerlinghausen B, Wolf T. Extended survival of patients on long-term lithium treatment. Can J Psychiatry 1995;40:241-246

Ahrens B, Müller-Oerlinghausen B, Schou M, Wolf T, Alda M, Grof E, Grof P, Lenz G, Simhandl C, Thau K, Vestergaard P, Wolf R, Möller HJ. Excess cardiovascular and suicide mortality of affective disorders may be reduced by lithium prophylaxis. J Affect Disord 1995;33:67-75

Ahrens B, Berghöfer A, Wolf T, Müller-Oerlinghausen B. Suicide attempts, age and duration of illness in recurrent affective disorders. J Affective Disord 1995;36:43-49

Ahrens B, Müller-Oerlinghausen B, Grof P. Length of lithium treatment needed to eliminate the high mortality of affective disorders. Br J Psychiatr 1993;163 (suppl.21):27-29

Angst J, Angst F, Gerber-Werder R, Gamma A. Suicide in 406 mood-disorder patients with and without long-term medication: a 40 to 44 years’ follow-up. Arch Suicide Res 2005;9:279-300

Berghöfer A. Lithium and suicide. BMJ 2013;347: f4449

Berghöfer A. Research explained. Lithium in the prevention of suicide in mood disorders. updated systematic review and meta-analysis. Student BMJ 2013;21: f5578

Blüml V, Regier MD, Hlavin G, Rockett IRH, König F, Vyssoki B, Bschor T, Kapusta ND. Lithium in the public water supply and suicide mortality in Texas. J Psychiatr Res 2013;47:407-411

Blüml V, Helbich M, Mayr M, Turnwald R, Vyssoki B, Lewitzka U, Hartung S, Plener PL, Fegert JM, Kapusta ND

Antidepressant sales and regional variations of suicide mortality in Germany

J Psychiatr Res 2016 Dec 13;87:88-94. doi: 10.1016/j.jpsychires.2016.12.013. [Epub ahead of print]

Brodersen A, Licht RW, Vestergaard P, Olesen AV, Mortensen PB. Sixteen-year mortality in patients with affective disorder commenced on lithium. Br J Psychiatry 2000;176:429-433

Bronisch T, Brunner J, Bondy B, Rujescu D, Bishof G, Heuser I, Muller-Oerlinghausen B, Hawellek B, Maier W, Rao ML, Felber W, Lewitzka U, Oehler J, Broocks A, Hohagen F, Lauterbach E. A multicenter study about neurobiology of suicidal behavior: design, development, and preliminary results. Arch Suicide Res 2005;9:19-26

de Lara CL, Dumais A, Rouleau G, Lesage A, Dumont M, Chawky N, Alda M, Benkelfat C, Turecki G. STin2 Variant and Family History of Suicide as Significant Predictors of Suicide Completion in Major Depression. Biol Psychiatry 2005 Aug 24; [Epub ahead of print]

Dumais A, Lesage AD, Alda M, Rouleau G, Dumont M, Chawky N, Roy M, Mann JJ, Benkelfat C, Turecki G. Risk factors for suicide completion in major depression: a case-control study of impulsive and aggressive behaviors in men. Am J Psychiatry 2005;162:2116-2124

Felber W. [Lithium prophylaxis and suicide prervention] In: M Wolfersdorf, WP Kaschka (eds). [Suici­dality – The Bio­logical Dimension]. Tropon-Symposium, Bd. X.. Berlin, Hei­delberg, New York: Springer, 1995; 157-174 (german)

Felber W, Kyber A. Suicides and parasuicides throughout and out of lithium prophylaxis. In: B Müller-Oerlinghau­sen, A Berghöfer (eds): Ziele und Ergeb­nisse der medika­mentösen Prophylaxe affektiver Psychosen. Stuttgart, New York: Thieme, 1994; 53-59 (german)

Kyber A, Felber W, König L. Does lithium prevent sui­cides and suicidal attempts? Pharmacopsychiat 1992;25:108

Lauterbach E, Felber W, Müller-Oerlinghausen B, Ahrens B, Bronisch T, Meyer T, Kilb B, Lewitzka U, Hawellek B, Quante A, Richter K, Broocks A, Hohagen F. Adjunctive lithium treatment in the prevention of suicidal behaviour in depressive disorders: a randomised, placebo-controlled, 1-year trial. Acta Psychiatr Scand 2008;118:469-479

Lauterbach E, Ahrens B, Felber W, Oerlinghausen BM, Kilb B, Bischof G, Heuser I, Werner P, Hawellek B, Maier W, Lewitzka U, Pogarell O, Hegerl U, Bronisch T, Richter K, Niklewski G, Broocks A, Hohagen F. Suicide prevention by lithium SUPLI–challenges of a multi-center prospective study. Arch Suicide Res 2005;9:27-34

Lewitzka U, Jabs B, Fülle M, Holthoff V, Juckel G, Uhl I, Kittel-Schneider S, Reif A, Reif-Leonhard C, Gruber O, Djawid B, Goodday S, Haussmann R, Pfennig A, Ritter P, Conell J, Severus E, Bauer M. Does lithium reduce acute suicidal ideation and behavior? A protocol for a randomized, placebo-controlled multicenter trial of lithium plus treatment as usual (TAU) in patients with suicidal major depressive episode. BMC Psychiatry. 2015 May 19;15:117

Lewitzka U, Severus E, Bauer R, Ritter P, Müller-Oerlinghausen B, Bauer M. The suicide prevention effect of lithium: more than 20 years of evidence – a narrative review. Int J Bipolar Disord. 2015 Dec;3(1):32. doi: 10.1186/s40345-015-0032-2. Epub 2015 Jul 18

Lewitzka U, Bauer M. What Role Does (Should) Lithium Play in Suicide Treatment/Prevention? Psychiatric Times, 2014; 10-15

Lewitzka U, Bauer M, Felber W, Müller-Oerlinghausen B. Anti-suicidal effect of lithium: current state of research and its clinical implications for the long-term treatment of affective disorders. Nervenarzt. 2013 Mar;84(3):294-306. German

McGirr A, Renaud J, Seguin M, Alda M, Benkelfat C, Lesage A, Turecki G. An examination of DSM-IV depressive symptoms and risk for suicide completion in major depressive disorder: a psychological autopsy study. J Affect Disord 2007;97:203-209

McGirr A, Seguin M, Renaud J, Benkelfat C, Alda M, Turecki G. Gender and risk factors for suicide: evidence for heterogeneity in predisposing mechanisms in a psychological autopsy study. J Clin Psychiatry 2006;67:1612-1617

Müller-Oerlinghausen B, Lewitzka U. Lithium reduces pathological aggression and suicidality: a mini-review. Neuropsychobiology 2010;62:43-49

Müller-Oerlinghausen B, Ahrens B, Felber W. The suicide-preventive and mortality-reducing effect of lithium. In: Bauer M, Grof P, Müller-Oerlinghausen B (Eds.) Lithium in Neuropsychiatry. Informa healthcare 2006

Mueller-Oerlinghausen B, Felber W, Berghofer A, Lauterbach E, Ahrens B. The impact of lithium long-term medication on suicidal behavior and mortality of bipolar patients. Arch Suicide Res 2005;9:307-319

Müller-Oerlinghausen B, Roggenbach J, Franke L. Serotonergic platelet markers of suicidal behavior–do they really exist? J Affect Disord 2004;79:13-24

Müller-Oerlinghausen B. How should findings on antisuicidal effects of lithium be integrated into practical treatment decisions? Eur Arch Psychiatry Clin Neurosci 2003;253:126-131

Müller-Oerlinghausen B, Berghöfer A, Ahrens B. The antisuicidal and mortality-reducing effect of lithium prophylaxis: consequences for guidelines in clinical psychiatry. Can J Psychiatry 2003;48:433-439

Müller-Oerlinghausen B, Berghöfer A. Antidepressants and suicidal risk. J Clin Psychiatr 1999;60 (suppl.2):94-99

Müller-Oerlinghausen B, Wolf T, Ahrens B, Glaenz T, Schou M, Grof E, Grof P, Lenz G, Simhandl C, Thau K, Vestergaard P, Wolf R. Mortality of patients who dropped out from regular lithium prophylaxis: a collaborative study by the International Group for the Study of Lithium-Treated patients (IGSLi). Acta Psychiatr Scand 1996;94:344-347

Müller-Oerlinghausen B, Wolf T, Ahrens B, Schou M, Grof E, Grof P, Lenz G, Simhandl C, Thau K, Wolf R. Mortality during initial and during later lithium treatment: a collaborative study by the International Group for the Study of Lithium-treated Patients (IGSLi). Acta Psychiatr Scand 1994;90:295-297

Müller-Oerlinghausen B. Die IGSLI-Studie zur Mortalität Lithium-behandelter Patienten mit affektiven Psychosen. In: Müller-Oerlinghausen B, Berghöfer A (Hrsg.) Ziele und Ergebnisse der medikamentösen Prophylaxe affektiver Psychosen. Georg Thieme Verlag Stuttgart, 1994;S. 35-40

Müller-Oerlinghausen B, Ahrens B, Grof E, Grof P, Lenz G, Schou M, Simhandl C, Thau K, Volk J, Wolf R, Wolf T. The effect of long-term lithium treatment on the mortality of patients with manic-depressive and schizoaffective illness. Acta Psychiatr Scand 1992;86:218-222

Müller-Oerlinghausen B, Müser-Causemann B, Volk J. Suicides and parasuicides in a high-risk patients group on and off lithium long-term medication. J Affect Disord 1992;25:261-269

Müller-Oerlinghausen B, Ahrens B, Volk J, Grof P, Grof E, Schou M, Vestergaard P, Lenz G, Simhandl C, Thau K, Wolf R. Letter: Reduced mortality of manic-depressive patients in long-term lithium treatment: an international collaborative study by IGSLi. Psychiat Res 1991;36:329-331

Nilsson A. Mortality in recurrent mood disorders during periods on and off lithium. A complete population study in 362 patients. Pharmacopsychiatry 1995;28:8-13

Rombold F, Lauterbach E, Felber W, Müller-Oerlinghausen B, Ahrens B, Bronisch T, Kilb B, Lewitzka U, Richter K, Broocks A, Heuser I, Hohagen F, Quante A. Adjunctive lithium treatment in the prevention of suicidal behavior in patients with depression and comorbid personality disorders. Int J Psychiatry Clin Pract 2014;18(4):300-3

Wolf T, Müller-Oerlinghausen B, Ahrens B, Grof P, Schou M, Felber W, Grof E, Lenz G, Nilsson A, Simhandl C, Thau K, Vestergaard P, Wolf R. How to interpret findings on mortality of long-term lithium treated manic-depressive patients?! Critique of different methodological approaches. J Affect Disord 1996;39:127-132

Alda M. Lithium in the treatment of bipolar disorder: pharmacology and pharmacogenetics. Mol Psychiatry 2015

Alda M, Shao L, Wang JF, Lopez de LC, Jaitovich-Groisman I, Lebel V, Sun X, Duffy A, Grof P, Rouleau GA, Turecki G, Young LT. Alterations in phosphorylated cAMP response element-binding protein (pCREB) signaling: an endophenotype of lithium-responsive bipolar disorder? Bipolar Disord 2013; 15: 824-831.

Alda M, Grof P, Rouleau GA, Turecki G, Young LT. Investigating responders to lithium prophylaxis as a strategy for mapping susceptibility genes for bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2005 Jul;29(6):1038-1045

Alda M. Pharmacogenetic aspects of bipolar disorder. Pharmacogenomics 2003;4:35-40

Alda M. Genetic factors and response to prophylactic treatment in bipolar disorder. In: Lerer B (ed) Pharmacogenetics of Psychotropics Drugs. Cambridge University Press, Cambridge, 2002

Alda M, Keller D, Grof E, Turecki G, Cavazzoni P, Duffy A, Rouleau GA, Grof P, Young LT. Is lithium response related to gs_ levels in transformed lymphoblasts from subjects with bipolar disorder? J Aff Disord 2001;65:117-122

Alda M. Genetic factors and treatment of mood disorders. Bipolar Disord 2001;3:318-324

Alda M, Grof P. Genetics and lithium response in bipolar disorders. In: Soares JC, Gershon S (ed) Basic Mechanisms and Therapeutic Implications of Bipolar Disorder. Marcel Dekker, NY, 2000

Alda M, Turecki G, Grof P, Cavazzoni P, Duffy A, Grof E, Ahrens B, Berghöfer A, Müller-Oerlinghausen B, Dvorakova M, Libigerova E, Vojtechovsky M, Zvolsky P, Joober R, Nilsson A, Prochazka H, Licht RW, Rasmussen NA, Schou M, Vestergaard P, Holzinger A, Schumann C, Thau K, Rouleau GA. Association and linkage studies of CRH and PENK genes in bipolar disorder: a collaborative IGSLI study. Am J Medical Genetics 2000;96:178-181

Alda M, Grof P, Ravindran L, Cavazzoni P, Duffy A, Grof E, Zvolsky P, Wilson J. Anticipation in bipolar illness: Is age at onset a valid criterion? Am J Med Gen 2000;96:804-807

Alda M, Cavazzoni P, Grof P. Treatment response to prophylactic lithium and family history of psychiatric disorders (letter to the editor). Biol Psychiatry 1999;45:1078

Alda M. Pharmacogenetics of lithium response in bipolar disorder. J Psychiatr Neurosci 1999;24:154-158

Alda M, Grof P, Grof E. MN blood groups and bipolar disorder: evidence of genotypic association and Hardy-Weinberg disequilibrium. Biol Psychiatry 1998;44:361-363

Alda M. Bipolar disorder: from families to genes. Can J Psychiatry 1997;42:378-387

Alda M, Turecki G, Grof P, Ahrens B, Berghöfer A, Cavazzoni P, Duffy A, Dvorakova M, Grof E, Holzinger A, Libigerova E, Licht RW, Martin B, Müller-Oerlinghausen B, Nilsson A, Prochazka H, Rasmussen NA, Rouleau GA, Schou M, Schumann C, Thau K, Vestergaard P, Vojtechovsky M, Zvolsky P. Molecular genetic investigations of candidate loci in lithium responsive bipolar disorder – a study by IGSLI. Europ Neuropsychopharmacol 1997;7 (suppl.2):S177

Alda M, Grof E, Cavazzoni P, Duffy A, Martin R, Ravindran L, Grof P. Autosomal recessive inheritance in families of responders to lithium prophylaxis. J Aff Disord 1997;44:153-157

Alda M, Grof P, Grof E, Zvolsky P, Walsh M. Mode of inheritance in families of patients with lithium-responsive affective disorders. Acta Psychiatr Scand 1994;90:304-310

Alda M, Grof P, Cameron P. Lithium as a tool in genetic research. In: Birch N (ed) Lithium in Medicine and Biology. Marius Press, 1993

Alda M, Zvolsky P, Grof P, Walsh M. Prophylactic lithium response and genetics of primary affective disorders. In: Kuhne GE (ed) Aktuelle Apekte der Psychiatrie. Universitatsverlag Jena, 1991

Cavazzoni P, Grof P, Duffy A, Grof E, Muller-Oerlinghausen B, Berghöfer A, Ahrens B, Zvolsky P, Robertson C, Davis A, Hajek T, Alda M. Heterogeneity of the risk of suicidal behavior in bipolar-spectrum disorders. Bipolar Disord. 2007;9:377-385

Cavazzoni P, Alda M, Turecki G, Rouleau G, Grof E, Martin R, Duffy A, Grof P. Lithium-responsive affective disorders: no association with the tyrosine hydroxylase gene. Psychiatry Res 1996; 64:91-96

Cruceanu C, Alda M, Dion PA, Turecki G, Rouleau GA. No evidence for GADL1 variation as a bipolar disorder susceptibility factor in a Caucasian lithium-responsive cohort. Am J Psychiatry 2015; 172: 94-95

Cruceanu C, Ambalavanan A, Spiegelman D, Gauthier J, Lafreniere RG, Dion PA, Alda M, Turecki G, Rouleau GA. Family-based exome-sequencing approach identifies rare susceptibility variants for lithium-responsive bipolar disorder. Genome 2013; 56: 634-640

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